Research

Energy balance

A 6-week Mediterranean diet combined with 5 days of semi-fasting (600-700 kcal) produces weight loss and body composition improvements equivalent to a standard hypocaloric Mediterranean diet without fasting.

You can lose weight effectively by simply reducing your daily calories by 500 kcal while following a Mediterranean diet pattern. Adding a 5-day semi-fast period (consuming 600-700 kcal of liquid/pureed meals) does not provide a significant advantage in weight loss over the standard diet alone. If you choose to try the semi-fast, be aware that it requires significant preparation and may not be sustainable for everyone long-term.

ModerateQualifiesMEDIUM confidence
The low calorie Mediterranean diet and the low calorie Mediterranean diet + semi-fast diet used in this study appear to be equally as effective in decreasing body weight, fat mass, visceral fat mass and waist circumference.
Ana Molina Jiménez et al. · Mediterranean Journal of Nutrition and Metabolism · 2019

Why this rating

Randomized controlled trial, but small sample size (n=42), short duration (6 weeks), and lack of long-term follow-up limit generalizability.

Source

The Mediterranean diet pattern with intermittent semi-fasting may facilitate weight loss: randomised controlled trial

Ana Molina Jiménez et al. · Mediterranean Journal of Nutrition and Metabolism · 2019

DOI 10.3233/mnm-180257

rct · n=42Cited 5×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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