Research
Energy balance
Lactobacillus sp. supplementation is safe and well-tolerated in non-comorbid obese individuals, with no significant adverse events reported.
You can take Lactobacillus probiotics with confidence regarding safety. Clinical trials show they are well-tolerated with no significant increase in side effects compared to a placebo.
GoodSupportsHIGH confidence
No significant adverse events were identified in either the intervention or placebo groups... Mild adverse effects, including diarrhea, skin rash, and abdominal discomfort, were occasionally reported but were not directly attributed to the probiotic supplementation.
Why this rating
Consistent reporting of safety across 12 trials.
Source
Probiotic Lactobacillus sp. as a strategy for modulation of non-comorbid obesity: A systematic meta-analysis and GRADE assessment of randomized controlled trials
Juan Alessandro Jeremis Maruli Nura Lele et al. · Narra J · 2025
DOI 10.52225/narra.v5i2.1562
Meta-analysis · 12 studiesCited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Lactobacillus sp. probiotic supplementation significantly reduces body mass index, body weight, waist and hip circumference, and visceral/subcutaneous fat mass in non-comorbid obese individuals compared to placebo.Good
- Lactobacillus sp. supplementation significantly decreases leptin levels and increases adiponectin levels in non-comorbid obese individuals.Moderate
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