Research

Micronutrients & recovery

Oral magnesium supplementation (365 mg elemental magnesium daily for 3 months) significantly improves insulin resistance, HOMA-IR, and metabolic markers in hypomagnesemic, obese, pre-diabetic patients with mild-to-moderate chronic kidney disease.

If you have early-stage kidney disease, are overweight, and have pre-diabetes, getting your magnesium levels checked is a low-cost, high-value step. If you are deficient, taking 365 mg of elemental magnesium daily, alongside a kidney-friendly diet and light exercise, can significantly improve your body's ability to handle insulin and sugar.

GoodSupportsHIGH confidence
Our data support the argument that magnesium supplementation improves the metabolic status in hypomagnesemic CKD patients with pre-diabetes and obesity.
Ömer Toprak et al. · Kidney & Blood Pressure Research · 2017

Why this rating

Randomized, double-blind, placebo-controlled trial with a clear primary endpoint, though limited to a single center and specific subgroup.

Source

Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study

Ömer Toprak et al. · Kidney & Blood Pressure Research · 2017

rct · n=128Cited 29,696×
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