Research

Mixed

High body mass index (BMI) is a causal risk factor for a broad spectrum of chronic diseases, including cardiovascular disease, diabetes, chronic kidney disease, multiple cancers, and musculoskeletal disorders, resulting in significant global mortality and disease burden.

Maintaining a BMI within the 20-25 kg/m2 range is associated with the lowest all-cause mortality risk. This is not just about weight but about reducing the risk of major chronic diseases like heart disease, diabetes, and certain cancers. Public health surveillance and evidence-based interventions are critical to addressing this growing burden.

StrongSupportsVERY_HIGH confidence
Epidemiological studies have identified high body mass index (BMI) as a risk factor for an expanding set of chronic diseases including cardiovascular disease, diabetes mellitus, chronic kidney disease, many cancers, and an array of musculoskeletal disorders.
The GBD 2015 Obesity Collaborators · New England Journal of Medicine · 2017

Why this rating

Based on a massive dataset of 67.8 million individuals across 195 countries using standardized GBD methods.

Source

Health Effects of Overweight and Obesity in 195 Countries over 25 Years

The GBD 2015 Obesity Collaborators · New England Journal of Medicine · 2017

cohort · n=67800000Cited 7,907×
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