Research

Mixed

Health benefits from prebiotics are mediated by the selective growth of specific microbial taxa and their metabolic products (e.g., SCFAs), rather than the substrate itself acting directly on host cells.

Prebiotics work by feeding specific gut bacteria. These bacteria then produce beneficial compounds (like short-chain fatty acids) that improve your health. You need a healthy gut microbiome for prebiotics to work.

StrongSupportsHIGH confidence
Prebiotics rely upon microbial metabolism. Non-microbial effects do not fit with our current classification.
Glenn R. Gibson et al. · Nature Reviews Gastroenterology & Hepatology · 2017

Why this rating

Consensus statement detailing the mechanistic requirements.

Source

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

Glenn R. Gibson et al. · Nature Reviews Gastroenterology & Hepatology · 2017

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