Mixed
A targeted, long-term, intensified multifactorial intervention (targeting hyperglycemia, hypertension, dyslipidemia, and microalbuminuria via behavior modification and pharmacotherapy) reduces the risk of cardiovascular and microvascular events by approximately 50% in patients with type 2 diabetes and microalbuminuria compared to conventional treatment.
If you have type 2 diabetes and early kidney warning signs (microalbuminuria), standard care may not be enough to protect your heart and kidneys. This study shows that a rigorous, long-term plan targeting blood sugar, blood pressure, cholesterol, and kidney health simultaneously—supported by frequent check-ins and lifestyle changes—can cut your risk of serious heart and kidney problems by half. It requires commitment to diet, exercise, and medications, but the long-term benefit is substantial.
A target-driven, long-term, intensified intervention aimed at multiple risk factors in patients with type 2 diabetes and microalbuminuria reduces the risk of cardiovascular and microvascular events by about 50 percent.
Why this rating
Randomized controlled trial (Steno-2) with long-term follow-up (mean 7.8 years) and composite clinical endpoints.
Source
Multifactorial Intervention and Cardiovascular Disease in Patients with Type 2 Diabetes
Peter Gæde et al. · New England Journal of Medicine · 2003
DOI 10.1056/nejmoa021778
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