Research
Macro partitioning
Replacing carbohydrates with Monounsaturated Fat (MUFA) lowers HbA1c and HOMA-IR, but does not significantly improve insulin secretion capacity (AIR) compared to PUFA.
Swapping carbohydrates for Monounsaturated Fats (like olive oil or avocados) can help lower HbA1c and improve insulin resistance. However, if your goal is to maximize insulin secretion capacity, Polyunsaturated Fats (PUFA) may offer an additional benefit that MUFA does not.
StrongQualifiesHIGH confidence
Replacing carbohydrate with MUFA lowered HbA1c (-0.09%; -0.12, -0.05; n = 23)... and homeostasis model assessment for insulin resistance (HOMA-IR) (-2.4%; -4.6, -0.3; n = 30). ... Based on gold-standard acute insulin response... PUFA significantly improved insulin secretion capacity... whether replacing carbohydrate, SFA, or even MUFA.
Why this rating
Meta-analysis of multiple trials.
Source
Effects of Saturated Fat, Polyunsaturated Fat, Monounsaturated Fat, and Carbohydrate on Glucose-Insulin Homeostasis: A Systematic Review and Meta-analysis of Randomised Controlled Feeding Trials
Fumiaki Imamura et al. · PLoS Medicine · 2016
Meta-analysis · 102 studiesCited 487×
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →