Macro partitioning
Replacing carbohydrates with Monounsaturated Fat (MUFA) lowers HbA1c and HOMA-IR, but does not significantly improve insulin secretion capacity (AIR) compared to PUFA.
Swapping carbohydrates for Monounsaturated Fats (like olive oil or avocados) can help lower HbA1c and improve insulin resistance. However, if your goal is to maximize insulin secretion capacity, Polyunsaturated Fats (PUFA) may offer an additional benefit that MUFA does not.
Replacing carbohydrate with MUFA lowered HbA1c (-0.09%; -0.12, -0.05; n = 23)... and homeostasis model assessment for insulin resistance (HOMA-IR) (-2.4%; -4.6, -0.3; n = 30). ... Based on gold-standard acute insulin response... PUFA significantly improved insulin secretion capacity... whether replacing carbohydrate, SFA, or even MUFA.
Why this rating
Meta-analysis of multiple trials.
Source
Effects of Saturated Fat, Polyunsaturated Fat, Monounsaturated Fat, and Carbohydrate on Glucose-Insulin Homeostasis: A Systematic Review and Meta-analysis of Randomised Controlled Feeding Trials
Fumiaki Imamura et al. · PLoS Medicine · 2016
DOI 10.1371/journal.pmed.1002087
More from this paper
- Replacing 5% of daily energy intake from carbohydrates with polyunsaturated fat (PUFA) significantly improves glucose-insulin homeostasis by lowering HbA1c, fasting insulin, and HOMA-IR, and improving insulin secretion capacity.Strong
- Replacing carbohydrates with Saturated Fat (SFA) has no significant effect on fasting glucose, though it may slightly lower fasting insulin.Strong
Related findings · Macro partitioning
- Total daily protein intake of 1.6 g/kg/day is sufficient for maximizing resistance training-induced muscle gains, with an upper confidence interval of 2.2 g/kg/day.Strong
- Resistance exercise training combined with sufficient dietary protein intake acts synergistically to maximize skeletal muscle hypertrophy, with protein intake saturating around 1.6 g/kg/day for general populations and potentially requiring 2.0-2.2 g/kg/day for resistance-trained individuals.Strong
- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →