Research
Mixed
Low-dose aspirin (75-160 mg/day) is recommended for primary prevention in individuals with a 10-year coronary heart disease risk of 10% or higher.
If your calculated 10-year risk of heart disease is 10% or higher, discuss taking low-dose aspirin (75-160 mg daily) with your doctor. The benefits of risk reduction generally outweigh the risks of bleeding for this group.
GoodConditionalHIGH confidence
Doses of 75–160 mg/d are as effective as higher doses. Therefore, consider 75–160 mg aspirin per day for persons at higher risk (especially those with 10-y risk of CHD of (cid:1)10%).
Why this rating
Based on US Preventive Services Task Force recommendations and meta-analyses cited.
Source
AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update
Thomas A. Pearson et al. · Circulation · 2002
DOI 10.1161/01.cir.0000020190.45892.75
clinical_guidelineCited 1,858×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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