Research

Mixed

All popular diets significantly reduce the LDL/HDL cholesterol ratio by approximately 10% at 1 year, regardless of macronutrient composition.

You do not need to follow a specific low-carb or low-fat protocol to improve your cholesterol ratio. The study shows that any popular diet, if adhered to, will improve your LDL/HDL ratio by about 10%. Focus on losing weight through a diet you can sustain, as the improvement in lipids is a consequence of that adherence and weight loss, not the specific macronutrient breakdown.

GoodSupportsHIGH confidence
Each diet significantly reduced the low-density lipoprotein/high-density lipoprotein (HDL) cholesterol ratio by approximately 10% (all P<.05), with no significant effects on blood pressure or glucose at 1 year.
Michael L. Dansinger et al. · JAMA · 2005

Why this rating

RCT design, but high attrition and self-reported adherence data limit the precision of the causal link to specific diets.

Source

Comparison of the Atkins, Ornish, Weight Watchers, and Zone Diets for Weight Loss and Heart Disease Risk Reduction

Michael L. Dansinger et al. · JAMA · 2005

DOI 10.1001/jama.293.1.43

rct · n=160Cited 1,738×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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