Micronutrients & recovery
Daily supplementation with 2000 IU of vitamin D3 does not reduce the incidence of invasive cancer or major cardiovascular events in adults aged 50+ (men) and 55+ (women) compared to placebo.
Taking 2000 IU of vitamin D3 daily will not prevent cancer or heart attacks in generally healthy older adults, according to this major study. While vitamin D is essential for bone health, this specific dose does not offer the broad disease-prevention benefits often marketed. Focus on proven strategies for cancer and heart health prevention rather than relying on this supplement for those outcomes.
Supplementation with vitamin D was not associated with a lower risk of either of the primary end points... cancer was diagnosed in 1617 participants (793 in the vitamin D group and 824 in the placebo group; hazard ratio, 0.96; 95% confidence interval [CI], 0.88 to 1.06; P = 0.47). A major cardiovascular event occurred in 805 participants (396 in the vitamin D group and 409 in the placebo group; hazard ratio, 0.97; 95% CI, 0.85 to 1.12; P = 0.69).
Why this rating
Large-scale, randomized, double-blind, placebo-controlled trial with high statistical power and long follow-up.
Source
Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease
JoAnn E. Manson et al. · New England Journal of Medicine · 2018
DOI 10.1056/nejmoa1809944
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