Research
Hormonal
Acute ingestion of 10g inulin-propionate ester increases postprandial PYY and GLP-1 levels and reduces energy intake by approximately 14% in healthy adults.
Taking 10g of this specific propionate ester with a meal can help you eat less during that meal by triggering fullness hormones. This effect happens about 4 hours after ingestion when the propionate reaches the colon.
GoodSupportsHIGH confidence
Acute ingestion of 10 g inulin-propionate ester significantly increased postprandial plasma PYY and GLP-1 and reduced energy intake.
Why this rating
Randomized controlled crossover study with 20 subjects, robust hormonal measurements.
Source
Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults
Edward S. Chambers et al. · Gut · 2014
DOI 10.1136/gutjnl-2014-307913
rct · n=60Cited 1,367×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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