Research
Hormonal
Higher serum lipopolysaccharide (LPS) levels in obese young subjects are positively correlated with BMI, waist circumference, and triglyceride levels, linking metabolic endotoxemia to central adiposity.
For young obese individuals, higher levels of gut-derived toxins (LPS) in the blood are linked to higher body weight, larger waist size, and higher triglycerides. This suggests that gut health plays a role in metabolic health beyond just calories.
ModerateSupportsMEDIUM confidence
A positive correlation was found between serum lipopolysaccharides and BMI (r = 0.46, p = 0.008), triglyceride levels (r = 0.44, p = 0.011) as well as waist circumference (r = 0.34, p = 0.040), being more evident in young obese females.
Why this rating
Observational study with small sample size; correlation does not prove causation.
Source
Gut Microbiota and Metabolic Endotoxemia in Young Obese Mexican Subjects
Romina Belén Radilla-Vázquez et al. · Obesity Facts · 2016
DOI 10.1159/000442479
cross_sectional · n=64Cited 1,198×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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