Hormonal
Faecalibacterium prausnitzii levels are significantly lower in obese individuals with Type 2 Diabetes and are negatively correlated with inflammatory markers (hs-CRP, IL-6), suggesting its role in reducing low-grade inflammation independently of calorie intake.
Low levels of Faecalibacterium prausnitzii are linked to higher inflammation in obese people with diabetes. Surgery helps restore this bacteria, which may help lower inflammation. This benefit appears to happen regardless of how much the patient eats, suggesting the surgery itself creates a gut environment that supports this beneficial bacteria.
Faecalibacterium prausnitzii species was lower in subjects with diabetes and associated negatively with inflammatory markers at M0 and throughout the follow-up after surgery independently of changes in food intake.
Why this rating
Strong statistical correlation (Spearman Rs) reported, but observational nature limits causal inference.
Source
Differential Adaptation of Human Gut Microbiota to Bariatric Surgery–Induced Weight Loss
Jean‐Pierre Furet et al. · Diabetes · 2010
DOI 10.2337/db10-0253
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