Mixed
Using electronically captured routine data (e.g., hospital episode statistics, clinical databases) for health technology assessment via randomised controlled trials is feasible and potentially cheaper than using purpose-designed data, provided clinical symptoms and signs are collected in sufficient detail.
For researchers designing health technology assessments, consider leveraging existing electronic patient records (like hospital episode statistics) to reduce costs and speed up recruitment. However, ensure that the routine data captures detailed clinical symptoms and signs, as administrative codes alone may not suffice for judging clinical effectiveness. Validate your local data systems' capability before committing to this approach.
Generally two-thirds of the research questions posed by health technology assessment through RCTs could be answered using routinely collected data... Routine data were found potentially to be cheaper to extract and analyse than designed data, and they also facilitate recruitment
Why this rating
Based on a systematic review of four replicated RCTs with independent statistical analysis, though validity of routine data is noted as 'suspect'.
Source
The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: a systematic review and economic evaluation
Joanna Picot et al. · Health Technology Assessment · 2009
DOI 10.3310/hta13410
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →