Micronutrients & recovery
Higher body mass index (BMI) causally leads to lower circulating 25-hydroxyvitamin D [25(OH)D] concentrations, primarily due to sequestration of vitamin D in adipose tissue.
If you have a higher BMI, your body stores more vitamin D in fat tissue, leaving less in your blood. This means standard vitamin D doses might not be enough for you. You likely need higher doses to reach healthy blood levels, and simply taking a standard supplement may not correct a deficiency if your weight is not addressed.
our study suggests that a higher BMI leads to lower 25(OH)D... the most likely explanation for the association is that the larger storage capacity for vitamin D in obese individuals leads to lower circulating 25-hydroxyvitamin D [25(OH)D] concentrations
Why this rating
Uses Mendelian Randomization with large cohorts (up to 42,024 participants) and replication in GIANT consortium (n=123,864), minimizing confounding.
Source
Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts
Karani S. Vimaleswaran et al. · PLoS Medicine · 2013
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