Research
Micronutrients & recovery
Marine n-3 supplementation may offer greater cardiovascular benefits for Black participants and those with low fish consumption.
If you are Black or eat very little fish, you might get more cardiovascular benefit from fish oil supplements than the average person. However, this is a hypothesis-generating finding and not definitive.
GoodConditionalMEDIUM confidence
Subgroup analyses showed a possible lower incidence of the primary cardiovascular end point with n−3 supplementation than with placebo among participants with low fish consumption... The suggestion of greater differences in the risk of myocardial infarction among blacks... is discussed in the Supplementary Appendix.
Why this rating
Based on subgroup analysis of a large RCT, but described as 'possible' and 'hypothesis-generating' by authors.
Source
Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer
JoAnn E. Manson et al. · New England Journal of Medicine · 2018
DOI 10.1056/nejmoa1811403
rct · n=25871Cited 952×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Supplementation with 1 g/day of marine n-3 fatty acids (containing 840 mg EPA/DHA) does not reduce the incidence of major cardiovascular events or invasive cancer in a general population at usual risk.Strong
- In a general population, 1 g/day marine n-3 supplementation significantly reduces the risk of total myocardial infarction.Strong
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