Research
Energy balance
Daily ingestion of capsinoids (nonpungent capsaicin analogs) for 6 weeks increases cold-induced thermogenesis (CIT) and energy expenditure, mimicking the effects of cold exposure on brown adipose tissue.
Taking 9 mg of capsinoids daily for 6 weeks can increase your body's ability to burn fat when exposed to cold, effectively boosting your energy expenditure. This offers a dietary way to potentially support weight management by activating brown fat.
GoodSupportsHIGH confidence
Similarly, daily ingestion of capsinoids for 6 weeks increased CIT.
Why this rating
Randomized, single-blinded, placebo-controlled crossover trial with objective metabolic measurements.
Source
Recruited brown adipose tissue as an antiobesity agent in humans
Takeshi Yoneshiro et al. · Journal of Clinical Investigation · 2013
DOI 10.1172/jci67803
crossover · n=51Cited 944×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →