Hormonal
Consuming approximately one fatty fish meal per week (approx. 5.5g n-3 fatty acids/month) is associated with a 50% reduction in the risk of primary cardiac arrest compared to no seafood intake.
To potentially lower your risk of primary cardiac arrest, aim to eat one serving of fatty fish (like salmon or mackerel) per week. This provides about 5.5 grams of n-3 fatty acids monthly, which the study links to a 50% lower risk compared to not eating seafood. This applies to healthy adults without prior heart disease.
Compared with no dietary intake of eicosapentaenoic acid (C20:5n-3) and docosahexaenoic acid (C22:6n-3), an intake of 5.5 g of n-3 fatty acids per month (the mean of the third quartile and the equivalent of one fatty fish meal per week) was associated with a 50% reduction in the risk of primary cardiac arrest (odds ratio [OR], 0.5; 95% confidence interval [CI], 0.4 to 0.8)
Why this rating
Population-based case-control study with strong biomarker validation (red blood cell membrane levels) and adjustment for confounders, though observational design limits causal inference.
Source
Dietary Intake and Cell Membrane Levels of Long-Chain n-3 Polyunsaturated Fatty Acids and the Risk of Primary Cardiac Arrest
David S. Siscovick · JAMA · 1995
DOI 10.1001/jama.1995.03530170043030
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