Research

Micronutrients & recovery

Enhancing the bioavailability of bioactive food compounds (such as polyphenols and PUFAs) through technologies like nanosystems, emulsification, or structural modification is necessary to ensure their bioefficacy and health benefits.

If you are consuming functional foods or supplements for specific health benefits, understand that 'more' is not always 'better' if your body cannot absorb it. The way food is processed (e.g., heating, grinding, emulsifying) and what it is eaten with (e.g., fats for lipophilic compounds) drastically changes whether you get the benefit. Look for products that utilize technologies designed to enhance absorption, such as nano-encapsulation or lipid-based delivery systems, especially for compounds known to have poor bioavailability like curcumin or certain polyphenols.

GoodSupportsHIGH confidence
Bioavailability is a key step in ensuring bioefficacy of bioactive food compounds or oral drugs... Bioefficacy may be improved through enhanced bioavailability. Therefore, several technologies have been developed to improve the bioavailability of xenobiotics, including structural modifications, nanotechnology and colloidal systems.
Maarit J. Rein et al. · British Journal of Clinical Pharmacology · 2012

Why this rating

The paper is a comprehensive review citing numerous primary studies, in vitro models, and human trials, though it notes that extensive work is still required for some interactions.

Source

Bioavailability of bioactive food compounds: a challenging journey to bioefficacy

Maarit J. Rein et al. · British Journal of Clinical Pharmacology · 2012

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