Mixed
Continuously high levels of exercise (e.g., marathon running) may have detrimental effects on cardiovascular health, including increased coronary artery calcification, suggesting a U-shaped or J-shaped dose-response curve.
For most people, moderate exercise is optimal. If you are an endurance athlete, be aware that very high volumes (like multiple marathons per year for decades) may increase coronary calcification, though this does not necessarily mean higher event rates due to potentially more stable plaques. Consult a physician if you engage in extreme endurance training.
there is evidence to suggest that continuously high levels of exercise (e.g., marathon running) could have detrimental effects on cardiovascular health.
Why this rating
Based on observational studies and specific cohorts of endurance athletes; mechanisms are not fully elucidated.
Source
Cardiovascular Effects and Benefits of Exercise
Matthew A. Nystoriak et al. · Frontiers in Cardiovascular Medicine · 2018
DOI 10.3389/fcvm.2018.00135
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