Research
Hormonal
Tirzepatide reduces the incidence of heart failure hospitalizations, need for treatment intensification, and mortality due to cardiovascular causes in patients with heart failure and reduced ejection fraction.
If you have heart failure and reduced ejection fraction, Tirzepatide can reduce your risk of hospitalization and cardiovascular mortality.
GoodSupportsHIGH confidence
At the end of 52 weeks, there was a 38% lower incidence of heart failure hospitalizations, need for treatment intensification, and lower mortality due to cardiovascular causes.
Why this rating
Based on the SUMMIT trial.
Source
Medical Management of Obesity: Current Trends and Future Perspectives
Andrés Calderón et al. · Methodist DeBakey Cardiovascular Journal · 2025
DOI 10.14797/mdcvj.1503
narrative_reviewCited 4×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Liraglutide (3 mg once daily) produces a mean weight loss of 8% over 56 weeks in patients without diabetes.Good
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