Research
Energy balance
Obesity is associated with a gut microbiota composition characterized by a higher Firmicutes-to-Bacteroidetes ratio and an increased capacity for energy harvest, which contributes to host adiposity.
Your gut bacteria may be more efficient at extracting energy from food than those of lean individuals, potentially contributing to weight gain. While you cannot directly 'eat' a new microbiome, the paper suggests that weight loss and dietary changes can alter this composition, potentially reducing this efficiency.
GoodSupportsHIGH confidence
Studies of the effect of excess body fat on the abundances of different bacteria taxa in the gut generally show alterations in the gastrointestinal microbiota... obesity was associated with a depletion of Bacteroidetes, together with an enrichment in carbohydrate and lipid-utilizing genes in the microbiome as a whole.
Why this rating
Based on multiple human and animal studies cited, though human results show variability.
Source
Obesity and the human microbiome
Ruth E. Ley · Current Opinion in Gastroenterology · 2009
DOI 10.1097/mog.0b013e328333d751
narrative_reviewCited 771×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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