Research

Mixed

Social strain (negative quality of relationships) is a significant predictor of worsening physiological outcomes (inflammation, obesity) in midlife and late adulthood, often more so than social support.

Be mindful of the quality of your social relationships, not just the quantity. High-strain relationships (those causing stress or conflict) are linked to increased inflammation and obesity, particularly in midlife and old age. Prioritizing positive, low-strain interactions may be more beneficial for physiological health than maintaining numerous but stressful connections.

GoodSupportsMEDIUM confidence
We found evidence for social strain as a more significant predictor of (worsening) physiological outcomes than commonly examined social support measures hypothesized to improve health.
Yang Claire Yang et al. · Proceedings of the National Academy of Sciences · 2016

Why this rating

Longitudinal data with objective biomarkers, though effect sizes for strain are described as 'mildly increased' or 'moderate'.

Source

Social relationships and physiological determinants of longevity across the human life span

Yang Claire Yang et al. · Proceedings of the National Academy of Sciences · 2016

DOI 10.1073/pnas.1511085112

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DOI resolved against Crossref · corpus check 2026-06-10

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