Macro partitioning
Adherence to a Mediterranean diet (rich in fruits, vegetables, whole grains, legumes, olive oil, and low in red/cured meat) attenuates inflammation and oxidative stress, thereby modulating immunosenescence.
Adopting a Mediterranean-style diet, emphasizing plant-based foods, olive oil, and limiting red meat, can help reduce chronic inflammation associated with aging. This dietary pattern is linked to lower levels of inflammatory markers like CRP and IL-6.
The efficacy of this diet results as an attenuation of inflammation and oxidative stress, and from the maintenance of a condition of eubiosis of the microbiota... The Mediterranean diet down-regulates the levels of inflammatory mediators, such as soluble intercellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule (VCAM)-1, C reactive protein, and IL-6
Why this rating
The paper cites observational data and studies showing reduced inflammatory markers, but notes 'wide heterogeneity among human beings' as a barrier.
Source
Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention
Anna Aiello et al. · Frontiers in Immunology · 2019
DOI 10.3389/fimmu.2019.02247
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