Energy balance
The doubly labeled water method provides a valid and accurate measurement of energy expenditure in free-living humans when using moderate isotope doses and correcting for isotopic fractionation.
For accurate energy expenditure tracking in free-living individuals, the doubly labeled water method is the most reliable non-restrictive tool available, provided that moderate isotope doses are used and proper corrections for isotopic fractionation are applied.
The doubly labeled water method represents a valuable nonrestrictive method for measuring energy expenditure in free-living subjects.
Why this rating
High-precision validation study with multiple subjects and comparison to gold-standard respiratory gas exchange.
Source
Energy expenditure by doubly labeled water: validation in humans and proposed calculation
Dale A. Schoeller et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1986
DOI 10.1152/ajpregu.1986.250.5.r823
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →