Research

Mixed

A typical high-FODMAP diet increases the relative abundance of butyrate-producing Clostridium cluster XIVa and mucus-associated Akkermansia muciniphila compared to a low FODMAP diet.

Eating a diet higher in FODMAPs (typical Western/Australian diet) promotes the growth of beneficial bacteria like Clostridium cluster XIVa (butyrate producers) and Akkermansia muciniphila (mucus-associated) compared to a strict low FODMAP diet. This suggests that long-term strict restriction might deprive the gut of substrates needed to maintain these specific beneficial populations.

GoodSupportsHIGH confidence
the typical Australian diet increased relative abundance for butyrate-producing Clostridium cluster XIVa (median ratio 6.62; p<0.001) and mucus-associated Akkermansia muciniphila (19.3; p<0.001)... on the low FODMAP diet reduced Ruminococcus torques.
Emma P. Halmos et al. · Gut · 2014

Why this rating

Same study design as N1, robust statistical significance.

Source

Diets that differ in their FODMAP content alter the colonic luminal microenvironment

Emma P. Halmos et al. · Gut · 2014

DOI 10.1136/gutjnl-2014-307264

crossover · n=33Cited 672×
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DOI resolved against Crossref · corpus check 2026-06-10

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