Research
Micronutrients & recovery
Vitamin D3 supplementation at 4000 IU/day does not significantly reduce the risk of developing type 2 diabetes in adults at high risk who are not selected for vitamin D insufficiency.
If you are at high risk for type 2 diabetes, taking 4000 IU of Vitamin D3 daily will not significantly lower your risk of developing the disease unless you are severely deficient. Focus on proven lifestyle changes like weight management and physical activity instead of relying on this supplement for prevention.
StrongRefutesHIGH confidence
Among persons at high risk for type 2 diabetes not selected for vitamin D insufficiency, vitamin D3 supplementation at a dose of 4000 IU per day did not result in a significantly lower risk of diabetes than placebo.
Why this rating
Large, multicenter, randomized, double-blind, placebo-controlled clinical trial (RCT) with high statistical power.
Source
Vitamin D Supplementation and Prevention of Type 2 Diabetes
Anastassios G. Pittas et al. · New England Journal of Medicine · 2019
rct · n=2423Cited 657×
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