Energy balance
A primary care-led, very-low-calorie diet (825-853 kcal/day) can induce remission of type 2 diabetes, with remission rates directly correlating to the magnitude of weight loss (86% remission with >15% weight loss).
If you have early-stage type 2 diabetes, talk to your doctor about a medically supervised very low-calorie diet (around 800-850 calories/day). The goal is to lose at least 15kg (33lbs) if you weigh 100kg, or roughly 15% of your body weight. This specific level of weight loss has been shown to put diabetes into remission in the majority of cases by reducing fat in the liver and pancreas.
intervention group에 저열량식이(low calorie diet, 825-853 kcal/day; 59% carbohydrate, 13% fat, 26% protein, 2% fiber)를 주어 46%에서 당뇨병 완화를 달성하였다. 특히 10% 이상 체중 감소군에서는 57%의 당뇨병 완화를 보였고, 15% 이상 체중 감소군에서는 86%의 당뇨병 완화를 보여 체중을 10% 이상만 빼면... 당뇨병 또한 치료가 가능함을 알려준 연구이다.
Why this rating
Based on a large, randomized, open-label cluster trial (DiRECT) published in The Lancet, though the paper is a review summarizing it.
Source
Current Treatments on Obesity
Chul Jin Lee et al. · Daehan imsang geon-gang jeungjin hakoeji/Daehan imsang geon'gang jeungjin haghoeji · 2019
DOI 10.15384/kjhp.2019.19.4.171
More from this paper
- Long-term adherence to a Low-Carb High-Fat (LCHF) diet is difficult for most patients, leading to decreased efficacy over time compared to low-fat diets, although it may offer short-term benefits for diabetes management.Good
- GLP-1 receptor agonists (e.g., Liraglutide, Semaglutide) and dual/triple agonists are highly effective for weight loss and diabetes remission, acting on both homeostatic and hedonic appetite pathways, but require continuous use to maintain effects.Good
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
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