Micronutrients & recovery
Daily vitamin D3 supplementation (4000 IU) for 6 months significantly reduces insulin resistance and improves insulin sensitivity in South Asian women who are both vitamin D deficient and insulin resistant, but only when serum 25(OH)D levels reach at least 80 nmol/l.
If you are a South Asian woman with known insulin resistance and low Vitamin D, taking 4000 IU of Vitamin D3 daily for 6 months can significantly improve your insulin sensitivity. However, you must achieve a blood level of at least 80 nmol/l, which requires consistent daily intake. Do not expect results in the first 3 months; the metabolic benefit typically manifests after 6 months of sustained high-dose supplementation.
Significant improvements were seen in insulin sensitivity and IR (P=0.003 and 0.02, respectively), and fasting insulin decreased (P=0.02) with supplementation compared with placebo... IR was most improved when endpoint serum 25(OH)D reached >=80 nmol/l.
Why this rating
Randomized, placebo-controlled, double-blind trial with a specific, high-risk population, though sample size is moderate (n=42 vs 39).
Source
Vitamin D supplementation reduces insulin resistance in South Asian women living in New Zealand who are insulin resistant and vitamin D deficient – a randomised, placebo-controlled trial
Pamela R. von Hurst et al. · British Journal Of Nutrition · 2009
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