Mixed
Post-acute SARS-CoV-2 infection is associated with specific brain MRI changes (thalamic T2* signal, white matter diffusivity) and impaired executive/visuospatial cognitive performance, which correlate with the severity of the initial inflammatory response.
If you are experiencing 'brain fog' or difficulty with planning and spatial tasks after COVID-19, it may be linked to structural changes in your brain. Consider a neuropsychological evaluation to assess cognitive function, as these deficits are common and may require specific cognitive rehabilitation strategies.
Patients exhibited changes in the thalamus, posterior thalamic radiations and sagittal stratum on brain MRI and demonstrated impaired cognitive performance, specifically in the executive and visuospatial domains... Periventricular white matter hyperintensities (pWMH) and right thalamic T2* correlated with white cell count... in patients.
Why this rating
Observational data with matched controls; cognitive testing was standardized (MoCA).
Source
Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge
Betty Raman et al. · EClinicalMedicine · 2021
DOI 10.1016/j.eclinm.2020.100683
More from this paper
- Medium-term recovery from moderate-to-severe SARS-CoV-2 infection is characterized by persistent multi-organ MRI abnormalities, significantly reduced exercise capacity, and impaired cognitive performance, which correlate with the severity of the initial acute illness.Good
- Post-acute SARS-CoV-2 infection is associated with a higher burden of self-reported depression, anxiety, and impaired quality of life across all domains, independent of physical symptoms.Good
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