Micronutrients & recovery
Supplementation with 150 mg/day of quercetin for 6 weeks significantly reduces plasma concentrations of atherogenic oxidised LDL in overweight subjects with high cardiovascular disease risk traits.
For individuals with metabolic risk factors, 150mg of quercetin daily for 6 weeks can significantly lower oxidised LDL, a marker linked to heart disease risk. This benefit occurs even though quercetin has low bioavailability, suggesting its metabolites are effective. This is a specific benefit for high-risk individuals and not necessarily seen in healthy, normotensive populations.
Quercetin supplementation decreased serum concentrations of oxidised LDL by 170·8 (SD 328·5) ng/ml (P,0·001). This change was significantly different (P, 0·05) from the decrease by 88·8 (SD 360·3) ng/ml (P, 0·05) during placebo treatment
Why this rating
Same high-quality study design as N1.
Source
Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study
Sarah Egert et al. · British Journal Of Nutrition · 2009
DOI 10.1017/s0007114509359127
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