Research
Mixed
Combining moderate-to-vigorous aerobic exercise with 3.0 mg/day liraglutide yields superior weight loss maintenance and metabolic health improvements compared to either intervention alone or placebo.
To maintain weight loss effectively, combine daily 3.0 mg liraglutide with a structured exercise routine aiming for 150 minutes of moderate or 75 minutes of vigorous activity per week. This combination is significantly more effective for weight loss and metabolic health than using either method alone.
StrongSupportsVERY_HIGH confidence
A strategy combining exercise and liraglutide therapy improved healthy weight loss maintenance more than either treatment alone.
Why this rating
Randomized, head-to-head, placebo-controlled trial published in NEJM.
Source
Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined
J. Lundgren et al. · New England Journal of Medicine · 2021
rct · n=195Cited 460×
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