Research

Macro partitioning

Very-Low-Carbohydrate Diets (VLCDs, <10% energy or 20-50g carbs) produce significantly greater weight loss than standard Low-Carbohydrate Diets (LCDs) or Low-Fat Diets (LFDs) in T2DM patients.

If you are willing to restrict carbohydrates to 20-50 grams per day (less than 10% of your calories), you can expect significantly more weight loss (nearly 9.5 kg more than low-fat diets) than with standard low-carb or low-fat approaches. This is the most effective dietary strategy for weight loss in T2DM patients identified in this review, though maintaining such strict limits long-term is challenging.

GoodSupportsHIGH confidence
Interestingly, the reduction in body weight tended to be greater in the subgroup that used VLCD (WMD = -9.49 kg; 95% CI: -12.88, -6.09, P < 0.00001).
Shunhua Li et al. · International Journal of Endocrinology · 2021

Why this rating

Derived from subgroup analysis of the same 12 RCTs.

Source

Comparing the Efficacy and Safety of Low-Carbohydrate Diets with Low-Fat Diets for Type 2 Diabetes Mellitus Patients: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Shunhua Li et al. · International Journal of Endocrinology · 2021

Meta-analysis · 12 studiesCited 26×
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