Research
Mixed
Sleep deprivation increases the risk of cardiometabolic diseases (hypertension, type 2 diabetes, obesity) by promoting systemic inflammation, insulin resistance, and sympathetic nervous system overactivity.
Aim for 7-8 hours of sleep to protect your heart and metabolic health. Chronic sleep restriction (<6 hours) significantly increases your risk of obesity, type 2 diabetes, and hypertension by promoting inflammation and insulin resistance. Prioritizing sleep is a foundational strategy for preventing cardiometabolic disease.
StrongSupportsVERY_HIGH confidence
Sleep deprivation increases the risk for obesity (about 55% higher risk), insulin resistance, T2DM (28% higher risk), and hypertension (21% higher risk)... experimental sleep deprivation (acute or chronic) is accompanied by increased sympathetic outflow, with consequent higher blood pressure and heart rate.
Why this rating
Supported by robust prospective epidemiological data, experimental studies, and clear mechanistic pathways.
Source
Role of sleep deprivation in immune-related disease risk and outcomes
Sergio Garbarino et al. · Communications Biology · 2021
narrative_reviewCited 525×
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