Mixed
In individuals with pre-diabetes or metabolic syndrome, incorporating meal replacements into a weight loss intervention yields small, clinically important reductions in body weight, BMI, LDL-c, non-HDL-c, and systolic blood pressure compared to conventional food-based diets.
If you have pre-diabetes or metabolic syndrome, using meal replacements for 1-2 meals a day as part of a calorie-restricted diet will help you lose more weight and improve your cholesterol and blood pressure than just eating a standard healthy diet. Aim for replacements to make up about 28% of your daily calories. This is a short-term tool to jumpstart your health before transitioning to regular food.
The available evidence suggests that incorporating MRs into a weight loss intervention leads to small important reductions in body weight, BMI, LDL-c, non-HDL-c, and systolic blood pressure, and trivial reductions in waist circumference and HbA1c, beyond that seen with conventional food-based weight loss diets.
Why this rating
Certainty is graded as moderate to low due to imprecision and inconsistency (heterogeneity).
Source
Weight management using meal replacements and cardiometabolic risk reduction in individuals with pre‐diabetes and features of metabolic syndrome: A systematic review and meta‐analysis of randomized controlled trials
Jarvis C. Noronha et al. · Obesity Reviews · 2024
DOI 10.1111/obr.13751
Related findings · Mixed
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