Micronutrients & recovery
Therapeutic Vitamin D supplementation for verified deficiency (25(OH)D < 20 ng/mL) should use doses of 1,000–10,000 IU/day (or 50,000 IU/week) for 1-3 months, avoiding loading doses of 300,000 IU or higher.
If your blood test shows Vitamin D deficiency (<20 ng/mL), do not take a massive 'loading dose' of 300,000 IU. Instead, take 1,000-10,000 IU daily (or 50,000 IU weekly) for 1-3 months. Re-test your levels after 3 months and switch to a maintenance dose (800-2,000 IU/day) once you reach the target range of 30-50 ng/mL.
The therapeutic dose in severe depletion should be 1,000–10,000 IU/day (~50,000 IU/week), depending on the patient’s age and body weight. Loading doses of 300,000 IU and higher are not recommended, even for the treatment of severe deficiency
Why this rating
Based on expert consensus and clinical guidelines, though the paper notes limitations in RCTs for specific dosing regimens.
Source
Practical guidelines for the supplementation of vitamin D and the treatment of deficits in Central Europe — recommended vitamin D intakes in the general population and groups at risk of vitamin D deficiency
Paweł Płudowski et al. · Endokrynologia Polska · 2013
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