Research
Micronutrients & recovery
Hydroxytyrosol improves metabolic health in non-alcoholic fatty liver disease (NAFLD) and obesity by activating transcription factors (PPAR-α, Nrf2), inhibiting lipogenesis, and reducing hepatic inflammation and oxidative stress.
Hydroxytyrosol may support liver health and metabolic function, particularly in the context of a high-fat diet, by reducing inflammation and fat accumulation. While promising in animal studies, human data is still emerging. Focus on a balanced diet rich in olive oil for best results.
ModerateSupportsMEDIUM confidence
HTyr significantly improves metabolic impairments induced by HFD [73,74]. HTyr prevents early inflammatory events responsible for the onset of insulin resistance and steatosis, by reducing the hepatic inflammation and nitrosative/oxidative stress and restoring glucose homeostasis and intestinal barrier integrity [73].
Why this rating
Strong animal model evidence, limited human clinical trials.
Source
Hydroxytyrosol, Tyrosol and Derivatives and Their Potential Effects on Human Health
Ana Marković et al. · Molecules · 2019
narrative_reviewCited 517×
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