Mixed
A structured, virtual, community-based lifestyle intervention using meal replacements and behavioral support achieves weight loss (14-16%) and type 2 diabetes remission (43%) comparable to GLP-1 receptor agonist therapies.
To achieve significant weight loss and potentially reverse type 2 diabetes, consider a structured program that combines a temporary period of meal replacements with long-term behavioral support. Look for programs that offer frequent check-ins, community support, and a clear plan for transitioning back to regular food. This approach can be as effective as newer weight-loss drugs for many people, especially when sustained over 18 months.
REWIND, a virtual, community‐based program, resulted in an average loss of 16% of initial body weight at 6 months and 14% at 18 months... This degree of weight loss resulted in a marked improvement in glycemic control in people with type 2 diabetes, including diabetes remission in 43% of the diabetes participants at 18 months.
Why this rating
Prospective cohort study with no control group; self-reported weight; single geographic region.
Source
Lifestyle Change Interventions: Effectiveness of REWIND, a Virtual, Community‐Based Weight Management Program
Amy E. Rothberg et al. · Obesity Science & Practice · 2025
DOI 10.1002/osp4.70092
Related findings · Mixed
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