Mixed
Adherence to a Mediterranean diet supplemented with extra-virgin olive oil (EVOO) significantly reduces the incidence of invasive breast cancer in postmenopausal women at high cardiovascular risk compared to a control low-fat diet.
If you are a postmenopausal woman with cardiovascular risk factors, incorporating extra-virgin olive oil as a primary fat source (aiming for roughly 1 liter per week distributed across your meals) into a Mediterranean-style diet may significantly lower your risk of developing invasive breast cancer. This benefit appears driven by the polyphenols and monounsaturated fats in the oil, rather than just calorie reduction. Focus on high-quality EVOO and use it to replace saturated fats, rather than adding it on top of an already high-fat diet.
This is the first randomized trial finding an effect of a long-term dietary intervention on breast cancer incidence. Our results suggest a beneficial effect of a Mediterranean diet supplemented with extra-virgin olive oil in the primary prevention of breast cancer.
Why this rating
Randomized controlled trial design with blinded outcome assessment, but limited by a small number of incident cases (n=35) and relatively short follow-up (median 4.8 years).
Source
Mediterranean Diet and Invasive Breast Cancer Risk Among Women at High Cardiovascular Risk in the PREDIMED Trial
Estefanía Toledo et al. · JAMA Internal Medicine · 2015
DOI 10.1001/jamainternmed.2015.4838
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