Research
Micronutrients & recovery
Magnesium acts as a physiological calcium antagonist in the cardiovascular system, inhibiting L-type calcium channels and promoting vasodilation, which may help regulate blood pressure.
Adequate magnesium intake supports cardiovascular health by helping to regulate blood pressure through calcium channel inhibition and nitric oxide production.
GoodSupportsHIGH confidence
Mg2+ inhibits these channels, preventing Ca2+ overload and cell toxicity and thus exerting a myocardial protective effect... Many different mechanisms are involved in the Mg2+ vasodilation effect, among which the ability of Mg2+ to act as a natural calcium channel blocker [104] and to upregulate the endothelial nitric oxide synthase, thus increasing nitric oxide (NO) release [102].
Why this rating
Supported by multiple studies cited in the review regarding cardiovascular mechanisms.
Source
Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency
Diana Fiorentini et al. · Nutrients · 2021
narrative_reviewCited 502×
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