Research
Mixed
Diabetes increases susceptibility to Covid-19 through mechanisms including aggravated inflammatory storms, immune dysfunction, lung injury, and increased ACE2 expression.
Diabetes contributes to severe Covid-19 through chronic inflammation, immune issues, lung injury, and higher ACE2 expression. Good glycemic control and medical care for diabetes are important for reducing risk.
GoodSupportsHIGH confidence
Individuals with diabetes are generally affected by a low-grade chronic inflammation, which might facilitate the cytokine storms, contributing to the severe outcomes of Covid-19 and the eventual death.
Why this rating
Supported by multiple studies cited in the review.
Source
Obesity and diabetes as high‐risk factors for severe coronavirus disease 2019 (<scp>Covid</scp>‐19)
Yue Zhou et al. · Diabetes/Metabolism Research and Reviews · 2020
DOI 10.1002/dmrr.3377
narrative_reviewCited 501×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Obesity and diabetes are high-risk factors for severe coronavirus disease 2019 (Covid-19), leading to increased morbidity, mortality, and progression to respiratory failure.Good
- Obesity increases susceptibility to Covid-19 through mechanisms including chronic inflammation, immune dysfunction, altered lung mechanics, and increased ACE2 expression.Good
Related findings · Mixed
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