Research
Macro partitioning
Circulating levels of soluble CD36 (sCD36) are abnormally elevated in NAFLD patients and positively correlate with the histological grade of hepatic steatosis, suggesting its utility as a biomarker.
Soluble CD36 levels in the blood may serve as a biomarker to assess the severity of fatty liver disease. This is a diagnostic tool rather than a treatment target for patients at this stage.
GoodSupportsHIGH confidence
Interestingly, circulating levels of a soluble form of CD36 (sCD36) are abnormally elevated in NAFLD patients and positively correlate with the histological grade of hepatic steatosis.
Why this rating
Based on clinical studies cited in the review.
Source
Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver?
Patricia Rada et al. · Cell Death and Disease · 2020
DOI 10.1038/s41419-020-03003-w
narrative_reviewCited 496×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- CD36 fatty acid translocase drives hepatosteatosis onset and progression to NASH by increasing fatty acid influx into hepatocytes, making it a key driver of NAFLD pathogenesis.Good
- Saturated fatty acids (SFAs) are more hepatotoxic than unsaturated fatty acids (UFAs) because they induce ER stress, oxidative stress, and apoptosis more effectively.Good
Related findings · Macro partitioning
- Total daily protein intake of 1.6 g/kg/day is sufficient for maximizing resistance training-induced muscle gains, with an upper confidence interval of 2.2 g/kg/day.Strong
- Resistance exercise training combined with sufficient dietary protein intake acts synergistically to maximize skeletal muscle hypertrophy, with protein intake saturating around 1.6 g/kg/day for general populations and potentially requiring 2.0-2.2 g/kg/day for resistance-trained individuals.Strong
- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →