Mixed

The relationship between reactive oxygen species (ROS) and lifespan is complex and non-linear; while the Free Radical Theory of Aging posits that ROS accumulation causes aging, experimental evidence shows that both increasing and decreasing ROS levels can extend or shorten lifespan depending on the species and context, suggesting mild ROS elevation can be beneficial via redox signaling.

Do not assume that taking high-dose antioxidant supplements will automatically extend your lifespan. The science suggests that a moderate level of oxidative stress is necessary for cellular signaling and health. Instead of focusing solely on eliminating ROS, focus on overall healthspan factors like exercise, which naturally modulates ROS in a beneficial way. The relationship between ROS and aging is too complex for simple 'antioxidant = longevity' rules.