Research
Hormonal
Erythrocyte Plasma Membrane Redox System (PMRS) and Ascorbate Free Radical (AFR) reductase activity increase with age as a compensatory mechanism to maintain plasma ascorbic acid levels and minimize oxidative stress.
Your body naturally tries to protect itself from oxidative stress during aging by increasing certain enzyme activities in red blood cells to recycle Vitamin C. This is an internal biological process, not something you can directly control.
ModerateQualifiesMEDIUM confidence
Recently it was reported that in human erythrocytes the activity of PMRS along with the AFR reductase increases with the increase in age. This activation of PMRS and AFR reductase increases the ASC recycling in human plasma and reported as a compensatory/protective mechanism that operates to maintain the ASC level in plasma and thereby minimize oxidative stress during aging.
Why this rating
Cites specific research (Rizvi et al.) within a review.
Source
Markers of Oxidative Stress in Erythrocytes and Plasma During Aging in Humans
Kanti Bhooshan Pandey et al. · Oxidative Medicine and Cellular Longevity · 2009
DOI 10.4161/oxim.3.1.10476
narrative_reviewCited 446×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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