Research
Mixed
Caffeine enhances vigilance and cognitive performance during sleep deprivation and extended exhaustive exercise, primarily through CNS adenosine antagonism.
If you are facing a period of sleep deprivation, such as during military operations or intense training camps, caffeine can help you stay alert. A dose of 600-800 mg (or ~4 mg/kg) taken as chewing gum or capsules can maintain vigilance and reaction time when sleep is limited.
GoodSupportsHIGH confidence
It has been shown that caffeine can enhance vigilance during bouts of extended exhaustive exercise, as well as periods of sustained sleep deprivation.
Why this rating
Supported by multiple studies cited (McLellan, Lieberman), but context-specific.
Source
International society of sports nutrition position stand: caffeine and performance
Erica R. Goldstein et al. · Journal of the International Society of Sports Nutrition · 2010
DOI 10.1186/1550-2783-7-5
narrative_reviewCited 686×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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