Research

Macro partitioning

Higher intake of polyunsaturated fatty acids (PUFA), particularly linoleic acid (omega-6), and monounsaturated fatty acids (MUFA) is associated with lower total mortality and cause-specific mortality.

Increase your intake of polyunsaturated (PUFA) and monounsaturated (MUFA) fats. Sources include nuts, seeds, vegetable oils (like soybean, corn, and olive oil), and fish. Higher intake of these fats is linked to lower total mortality. Specifically, linoleic acid (omega-6) and MUFA show strong inverse associations with mortality. Replace saturated fats with these unsaturated fats for the best health outcomes.

StrongSupportsHIGH confidence
Intakes of PUFA and MUFA were inversely associated with total mortality... The HRs comparing extreme quintiles were 0.81... for PUFA and 0.89... for MUFA... Intake of linoleic acid, the most abundant omega-6 PUFA, showed strong inverse associations with total and most cause-specific mortality...
Dong D. Wang et al. · JAMA Internal Medicine · 2016

Why this rating

Large prospective cohort studies with long follow-up and rigorous adjustment.

Source

Association of Specific Dietary Fats With Total and Cause-Specific Mortality

Dong D. Wang et al. · JAMA Internal Medicine · 2016

cohort · n=126233Cited 433×
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