Research

Mixed

Combining behavioral counseling with pharmacotherapy (e.g., orlistat, sibutramine) or meal replacements significantly increases weight loss compared to counseling alone in primary care settings.

If lifestyle changes alone aren't getting you the results you want, ask your doctor about adding FDA-approved weight loss medications like Orlistat. Studies show this can double your weight loss compared to diet and exercise alone. Note: Some older drugs like Sibutramine are no longer available due to heart risks.

GoodSupportsHIGH confidence
Behavioral treatment can be provided in combination with pharmacotherapy, which approximately doubles the weight loss achieved
Bruce M. Wolfe et al. · Circulation Research · 2016

Why this rating

Supported by multiple randomized trials (Hauptman, Poston, Wadden) showing additive effects.

Source

Treatment of Obesity

Bruce M. Wolfe et al. · Circulation Research · 2016

book_chapterCited 635×
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