Research
Hormonal
Routine screening of serum 25(OH)D levels is not recommended for any population (children, adults, pregnant, obese, dark complexion) in the absence of established clinical indications.
Do not get your vitamin D levels tested unless you have a specific medical condition like hypocalcemia. The guideline states that no specific blood level has been proven to prevent disease, so testing will not change your advice: just take the standard recommended dose.
ModerateRefutesMEDIUM confidence
The panel suggests against routine 25(OH)D testing in all populations considered. No clinical trial evidence was found to support routine screening for 25(OH)D in the general population, nor in those with obesity or dark complexion.
Why this rating
Based on lack of evidence for threshold definition and ecological fallacy in subgroup analyses.
Source
Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline
Marie B. Demay et al. · The Journal of Clinical Endocrinology & Metabolism · 2024
DOI 10.1210/clinem/dgae290
Meta-analysisCited 431×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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