Mixed
High BMI is more strongly associated with adverse cardiovascular biomarker levels than physical inactivity, yet maintaining physical activity provides favorable biomarker profiles even within overweight or obese BMI categories.
Focus on maintaining a healthy body weight as the primary lever for improving cardiovascular biomarkers like CRP and cholesterol. However, do not neglect physical activity; even if you are overweight or obese, being physically active (≥1000 kcal/week) significantly improves your biomarker profile compared to being inactive. The best outcome is achieved by combining regular moderate activity with a normal BMI.
High BMI was more strongly related to adverse cardiovascular biomarker levels than physical inactivity. However, within BMI categories, physical activity was generally associated with more favorable cardiovascular biomarker levels than inactivity.
Why this rating
Large sample size (n=27,158), rigorous statistical adjustment, but cross-sectional design limits causal inference.
Source
Association of Physical Activity and Body Mass Index With Novel and Traditional Cardiovascular Biomarkers in Women
Samia Mora et al. · JAMA · 2006
DOI 10.1001/jama.295.12.1412
Related findings · Mixed
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