Research

Micronutrients & recovery

Daily supplementation of 1.5-2 g of EPA (a component of omega-3 fatty acids) effectively stimulates mood elevation and treats depression in human patients.

If you are treating depression with omega-3 supplements, aim for a daily intake containing 1.5 to 2 grams of EPA. Do not exceed 3 grams daily, as higher doses offer no additional mood benefits and may be unsafe if you take blood-thinning medications. Consult your doctor before starting.

ModerateSupportsMEDIUM confidence
In depressed patients, daily consumption of dietary supplements of omega-3 fatty acid that contain 1.5-2 g of EPA has been shown to stimulate mood elevation.
TS Sathyanarayana Rao et al. · Indian Journal of Psychiatry · 2008

Why this rating

The paper cites epidemiological data and clinical studies but notes that doses >3g show no better effects than placebos, suggesting a narrow therapeutic window.

Source

Understanding nutrition, depression and mental illnesses

TS Sathyanarayana Rao et al. · Indian Journal of Psychiatry · 2008

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